Post-study caffeine administration enhances memory consolidation in humans
Nature Neuroscience (2014). Published online 12 January 2014
Daniel Borota, et al.
It is currently not known whether caffeine has an enhancing effect on long-term memory in humans.
We used post-study caffeine administration to test its effect on memory consolidation using a behavioral discrimination task.
Caffeine enhanced performance 24 h after administration according to an inverted U-shaped dose-response curve; this effect was specific to consolidation and not retrieval.
We conclude that caffeine enhanced consolidation of long-term memories in humans.