TEDMED > The science of psilocybin

The science of psilocybin and its use to relieve suffering
TEDMED. Apr 20, 2016
Leading psychopharmacologist Roland Griffiths discloses the ways that psychedelic drugs can be used to create spiritually meaningful, personally transformative experiences for all patients, especially the terminally ill.


The Science of Psychedelics – with Michael Pollan
The Royal Institution. 2018

Scopolamine

Revisiting transdermal scopolamine for postoperative nausea and vomiting
Research and Reports in Transdermal Drug Delivery 13 August 2015 4:35—44
Pergolizzi JV
https://www.dovepress.com/revisiting-transdermal-scopolamine-for-postoperative-nausea-and-vomiti-peer-reviewed-article-RRTD

Postoperative nausea and vomiting (PONV) and postdischarge nausea and vomiting (PDNV) in ambulatory patients remain serious problems that affect a substantial subset of surgical patients.

Keywords: transdermal scopolamine, postoperative nausea and vomiting, antiemetic

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NIMH’s Dr. Maura Furey: Brain activity predicts response to scopolamine
2013
https://medicalxpress.com/news/2013-01-brain-response-scopolamine.html

Drug laws & treatment innovation

Effects of Schedule I drug laws on neuroscience research and treatment innovation
David J. Nutt, Leslie A. King and David E. Nichols
NATURE REVIEWS NEUROSCIENCE, AUGUST 2013, VOLUME 14: 577-585
http://www.nature.com/nrn/journal/v14/n8/full/nrn3530.html

draconian penalty

cannabis (marijuana)

lysergic acid diethylamide (LSD; also known as lysergide)

3,4-methyl- enedioxy-N-methylamphetamine (MDMA; also known as ecstasy)

psilocybin:  a hallucinogenic indole C12H17N2O4P obtained from a fungus (as Psilocybe mexicana or P. cubensis syn. Stropharia cubensis)

LSD has been used successfully to treat other addictions

there is no evidence that psychedelics have addictive properties

MDMA similarly has low dependence potential, although some chronic cannabis users can develop dependence

circular argument

in the United States, medical use of marijuana is legal in 18 states and in the District of Columbia.

cannabis was a prescription medication in the United Kingdom until the middle of the twentieth century

In practice, research with Schedule I drugs has almost completely ceased, with research into psychedelic drugs being particularly affected.

Δ9-tetrahydrocannabinol (THC), the psychoactive ingredient of cannabis that makes users ‘stoned’.

Overall, cannabis is less harmful than other popular drugs, such as alcohol.

related news release:
http://www.maps.org/media/David_Nutt_NRN_Press_release_June2013.pdf

related:
http://www.npr.org/blogs/health/2014/08/12/339822911/colorado-case-puts-workplace-drug-policies-to-the-test