The Invisible Universe Of The Human Microbiome
NPR. Nov 5, 2013
The next time you look in a mirror, think about this: In many ways you’re more microbe than human.
There are 10 times more cells from microorganisms like bacteria and fungi in and on our bodies than there are human cells.
But these tiny compatriots are invisible to the naked eye.
So we asked artist Ben Arthur to give us a guided tour of the rich universe of the human microbiome.
Cross-talk between neural stem cells and immune cells: the key to better brain repair?
Nat Neurosci. 2012 Jul 26;15(8):1078-87.
Kokaia Z, et al.
Lund Stem Cell Center, University Hospital, Lund, Sweden.
Systemic or intracerebral delivery of neural stem and progenitor cells (NSPCs) and activation of endogenous NSPCs hold much promise as potential treatments for diseases in the human CNS. Recent studies have shed new light on the interaction between the NSPCs and cells belonging to the innate and adaptive arms of the immune system. According to these studies, the immune cells can be both beneficial and detrimental for cell genesis from grafted and endogenous NSPCs in the CNS, and the NSPCs exert their beneficial effects not only by cell replacement but also by immunomodulation and trophic support. The cross-talk between immune cells and NSPCs and their progeny seems to determine both the efficacy of endogenous regenerative responses and the mechanism of action as well as the fate and functional integration of grafted NSPCs. Better understanding of the dialog between NSPCs and innate and adaptive immune cells is crucial for further development of effective strategies for CNS repair.
Immunology in the Gut Mucosa
Feb 5, 2013