Why are some people with coronavirus asymptomatic?

Why are some people with coronavirus asymptomatic — and what makes them so contagious?
Aug. 9, 2020
By Quentin Fottrell
https://www.marketwatch.com/story/why-are-some-people-with-coronavirus-asymptomatic-and-why-are-they-so-contagious-2020-08-08

“Many individuals with SARS-CoV-2 infection remained asymptomatic for a prolonged period, and viral load was similar to that in symptomatic patients. Therefore, isolation of infected persons should be performed regardless of symptoms.”

original paper:
Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea
JAMA Intern Med. August 6, 2020.
Seungjae Lee, MD, et al.
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2769235

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Age-Related Differences in Nasopharyngeal SARS-CoV-2 Levels

Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19)
JAMA Pediatr. Published online July 30, 2020.
Taylor Heald-Sargent, MD
https://jamanetwork.com/journals/jamapediatrics/fullarticle/2768952
children younger than 5 years with mild to moderate COVID-19 have high amounts of SARS-CoV-2 viral RNA in their nasopharynx compared with older children and adults. Our study is limited to detection of viral nucleic acid, rather than infectious virus, although SARS-CoV-2 pediatric studies reported a correlation between higher nucleic acid levels and the ability to culture infectious virus.5 Thus, young children can potentially be important drivers of SARS-CoV-2 spread in the general population, as has been demonstrated with respiratory syncytial virus, where children with high viral loads are more likely to transmit.

journalistic version:
https://www.newschannel5.com/rebound/safely-back-to-school/study-shows-children-could-be-super-spreaders-others-say-there-havent-been-enough-tests-conducted

Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US
JAMA. Published online July 29, 2020.
Katherine A. Auger, MD, et al.
https://jamanetwork.com/journals/jama/fullarticle/2769034

Editorial
COVID-19 and School Closures
JAMA. Published online July 29, 2020.
Julie M. Donohue, PhD
https://jamanetwork.com/journals/jama/fullarticle/2769033

Reopening K-12 Schools During the COVID-19 PandemicA Report From the National Academies of Sciences, Engineering, and Medicine
JAMA. Published online July 29, 2020.
Kenne A. Dibner, PhD
https://jamanetwork.com/journals/jama/fullarticle/2769036

AAP issues guidance on reopening schools
May 7, 2020
https://www.healio.com/news/pediatrics/20200507/aap-issues-guidance-on-reopening-schools

Dr. John Campbell: The Next Few Months

The next few months
July 17, 2020
Dr. John Campbell

Professor Jonathan Van-Tam
(England’s deputy chief medical officer)

“The reality is, until we get a vaccine, and only if we get a vaccine that is really capable of suppressing disease levels, will we ever be “out of this””

“From that perspective, we may have to live, and learn to live, with this virus in the long-term. Certainly for many months to come, if not years.”

We are still at the start of this.

Airborne Transmission of COVID-19

239 Scientists agree on Aerosolization transmission
July 8, 2020
Dr. John Campbell

original paper:
It is Time to Address Airborne Transmission of COVID-19
Lidia Morawska, Donald K Milton
Clinical Infectious Diseases. 6 July 2020
https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa939/5867798

Keywords: airborne transmission, airborne infection spread, coronavirus, COVID-19, SARS-CoV-2 virus

related:
April 8, 2020
https://www.businessinsider.com/loud-talking-singing-spread-coronavirus-further-than-6-feet-2020-3

Universitat de Barcelona: Coronavirus traces found in March 2019 sewage sample

Virus in Barcelona, March 2019
June 29, 2020
Dr. John Campbell

Detectan el SARS-CoV-2 en aguas residuales recogidas en Barcelona el 12 marzo de 2019
Universitat de Barcelona. June 26, 2020
https://www.ub.edu/web/ub/es/menu_eines/noticies/2020/06/042.html

Coronavirus traces found in March 2019 sewage sample, Spanish study shows
June 26, 2020
https://www.reuters.com/article/us-health-coronavirus-spain-science/coronavirus-traces-found-in-march-2019-sewage-sample-spanish-study-shows-idUSKBN23X2HQ